The C1 single-cell sequencer from Fluidigm revolutionised the field of life science research by enabling researchers to explore tumour heterogeneity to better understand, among other things, cancer pathologies and mechanisms — and how new treatment designs could stop them. One of the methods scientists use to do this is called single-cell mRNA sequencing, and the […]
CyTOF and mass-tag barcoding let Eli Zunder ask more questions and find new answers “There are so many different things we want to know about every cell,” says Eli Zunder, PhD and stem cell biologist at Stanford. “And I always want to measure more—more transcription factors, more cell signaling molecules, more cell surface proteins, with […]
In 2015 the life sciences pioneer Fluidigm introduced Polaris, a machine that enabled scientists to combine acute dose-response and time-course studies with complete molecular readouts in order to fulfil a wide range of functional genomic applications. This was a revolution in genomic and biological studies, one that let the scientific community take a collective step […]
How Will Greenleaf, ATAC-seq and C1 Open App are pioneering single-cell epigenetics The draw of single-cell analysis lies in scientists’ desire to understand how we, as biological systems, work. Discovery upon discovery leads to deeper questions about passive versus causal mutations, transcription mechanisms, pathway regulation, cellular function. It can get really complex, or begin to […]
How John Daley leverages mass cytometry in his 36-year career fighting against cancer One day in 1979, a young biochemistry graduate answered an ad in the Boston Globe: “For those of you who want clinical relevance in the work you’re doing, we have an immediate opening available for a graduate biophysics background or relevant experience to […]
In this profile video, Dr. Andrew Brooks and the team at RUCDR explain how the speed and accuracy of Fluidigm technology makes their mission possible. Producers: Colleen Maloney, Uli Cohen Director: Alec Cohen Agency: Moving Pictures
Pioneering life scientists use biological sequencing machines like the C1 from Fluidigm to study cellular growth and pathology to better understand how diseases like cancer, lupus, diabetes and many others affect cell populations. The ability to look at individual cells, rather than making assumptions based on a whole population, is enabling unprecedented understanding of these […]
COLLEEN MALONEY